RapamycinFungusV1, Main, Exploration, bibRecord, 001077

Aging is not programmed: genetic pseudo-program is a shadow of developmental growth.

Identifieur interne : 001077 ( Main/Exploration ); précédent : 001076; suivant : 001078

Aging is not programmed: genetic pseudo-program is a shadow of developmental growth.

Auteurs : Mikhail V. Blagosklonny [États-Unis]

Source :

Cell cycle (Georgetown, Tex.) [ 1551-4005 ] ; 2013.

RBID : pubmed:24240128

Descripteurs français

KwdFr :
- Animaux (MeSH), Croissance (génétique), Croissance (physiologie), Humains (MeSH), Levures (physiologie), Processus stochastiques (MeSH), Vieillissement (génétique), Vieillissement (physiologie), Vieillissement de la cellule (génétique).
MESH :
- génétique : Croissance, Vieillissement, Vieillissement de la cellule.
- physiologie : Croissance, Levures, Vieillissement.
- Animaux, Humains, Processus stochastiques.

English descriptors

KwdEn :
- Aging (genetics), Aging (physiology), Animals (MeSH), Cellular Senescence (genetics), Growth (genetics), Growth (physiology), Humans (MeSH), Stochastic Processes (MeSH), Yeasts (physiology).
MESH :
- genetics : Aging, Cellular Senescence, Growth.
- physiology : Aging, Growth, Yeasts.
- Animals, Humans, Stochastic Processes.

Abstract

Aging is not and cannot be programmed. Instead, aging is a continuation of developmental growth, driven by genetic pathways such as mTOR. Ironically, this is often misunderstood as a sort of programmed aging. In contrast, aging is a purposeless quasi-program or, figuratively, a shadow of actual programs.

DOI: 10.4161/cc.27188
PubMed: 24240128
PubMed Central: PMC3905065

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000F33
to stream Main, to step Curation: 000F33

Le document en format XML

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Aging is not programmed: genetic pseudo-program is a shadow of developmental growth.

Aging is not programmed: genetic pseudo-program is a shadow of developmental growth.

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